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This product is a comprehensive formula designed to address immune challenges and maintain normal inflammatory balance. It provides a blend of phytonutrients including skullcap, bee propolis, and turmeric for full spectrum support.

 


 
 

 

Overview

Inflammation is a natural part of the body’s immune response, a cascade triggered to protect the body and maintain normal tissue repair. This physiological response is part of the innate immune or non-specific immune system, a first line of defense comprising the cells and mechanisms that defend against unwanted organisms in a non-specific manner. The inflammatory cascade is mediated by eicosanoids. This product provides a blend of nutrients to maintain normal inflammatory balance, while helping to balance eicosanoid and cytokine metabolism.

 

Skullcap Root Extract†

An extract of the root of Scutellaria baicalensis, this popular Chinese botanical has been shown to modulate the immune system and support cardiovascular health.1 Skullcap possesses potent antioxidant properties, and research has shown it attenuates NFkB and inhibits COX-2 expression.13 According to a recent study, the botanical boosts immune response to certain threats2 and supports normal respiration by protecting airways and preserving normal mitochondrial function.3

 

Bee Propolis Extract†

Bees create propolis by collecting a resinous sap from trees and then mixing it with wax within the hive. Propolis contains a diverse variety of potent terpenes and benzoic, caffeic, cinnamic, and phenolic acids. It is also high in flavonoids, which may account for many of its health benefits. Caffeic acid phenethyl ester (CAPE), one of the main active components in propolis helps maintain normal inflammatory balance, protect against oxidative stress, inhibit lipoxygenase and both COX1 and COX2, balance the immune response, and down regulate NFkB production.4 Another study on endurance cyclists, showed CAPE has an immune protective effect by enhancing the temperature tolerance of immune cells during long, high intensity training sessions.5

 

Turmeric (Complete Turmeric Matrix)†

Whole-root turmeric and its active components have been used in traditional Ayurvedic medicine for centuries. In herbal medicine of old, practitioners used teas, tinctures and extracts of all types. In the 21st century, as research grew on the benefits of turmeric, the focus shifted to identifying and isolating one individual compound, curcumin, rather than delivering the comprehensive benefits of a matrix of turmeric bioactives. As a result, concentrating curcumin led to poor absorption and pharmaceutical methods were applied to bypass the gut and increase its bioavailability. The glaring disadvantage of applying this pharmaceutical model to botanicals is that it misses the benefits of other bioactives present within the turmeric matrix and their positive effects on the microbiome. New research on turmeric shows the additional bioactives in turmeric have additional benefits and enhance bioavailability. The Complete Turmeric Matrix includes compounds from the entire turmeric root, all working together as nature intended to deliver better results. The Complete Turmeric Matrix formulation contains standardized amounts of 45%–55% curcuminoids, 2%-6% turmerin protein and 3%-8% volatile oil, plus other components that make up the whole turmeric root. This matrix of bioactive compounds supports a healthy GI tract, creates a healthy microbiome, and helps maintain normal inflammatory balance.

Specifically, turmeric and its phytonutrients, like curcumin, have been shown to have strong NFkB-modulating properties and plays a crucial role in maintaining normal inflammatory balance. Studies have also shown it supports the health of the GI tract,6-7 and promotes both gastrointestinal mucos and bowel health.8 Curcumin has been shown to provide cardiovascular protection9 and to help modulate low mood and fatigue by supporting a normal immune response, normalizing oxidative stress, and preventing intestinal hyperpermeability.10 It has also been shown to hold promise in supporting respiratory health.11

 


 

Directions

4 capsules per day in divided doses or as recommended by your health care professional.

Does Not Contain
Gluten, corn, yeast, artificial colors or flavors.

Cautions
If you are pregnant or nursing, consult your physician before
taking this product.

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References

  1. Li-Weber M. New therapeutic aspects of flavones: the anticancer
    properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin. Cancer Treat Rev. 2009 Feb;35(1):57-68.

  2. Hour MJ, Huang SH, Chang CY, Lin YK, Wang CY, Chang YS, Lin
    CW. Baicalein, Ethyl Acetate, and Chloroform Extracts of Scutellaria baicalensis Inhibit the Neuraminidase Activity of Pandemic 2009 H1N1 and Seasonal Influenza A Viruses. Evid Based Complement Alternat Med. 2013;2013:750803.

  3. Mabalirajan U, Ahmad T, Rehman R, Leishangthem GD, Dinda
    AK, Agrawal A, Ghosh B, Sharma SK. Baicalein reduces airway injury in allergen and IL-13 induced airway inflammation. PLoS One. 2013 Apr 30;8(4):e62916.

4. Sforcin JM. Propolis and the immune system: a review. J Ethnopharmacol. 2007 Aug 15;113(1):1-14. Epub 2007 May 22.

5. Chen YJ, Huang AC, Chang HH, Liao HF, Jiang CM, Lai LY, Chan JT,
Chen YY, Chiang J. Caffeic acid phenethyl ester, an antioxidant from propolis, protects peripheral blood mononuclear cells of competitive cyclists against hyperthermal stress. J Food Sci. 2009 Aug;74(6):H162-7.

6. Kumar S, Ahuja V, Sankar MJ, Kumar A, Moss AC. Curcumin for
maintenance of remission in ulcerative colitis. Cochrane Database Syst Rev. 2012 Oct 17;10:CD008424.

7. Baliga MS, Joseph N, Venkataranganna MV, Saxena A, Ponemone
V, Fayad R. Curcumin, an active component of turmeric in the prevention and treatment of ulcerative colitis: preclinical and clinical observations. Food Funct. 2012 Nov;3(11):1109-17.

8. Bengmark S, Mesa MD, Gil A. Plant-derived health: the effects of turmeric and curcuminoids. Nutr Hosp. 2009 May-Jun;24(3):273-81.

9. Kapakos G, Youreva V, Srivastava AK. Cardiovascular protection by
curcumin: molecular aspects. Indian J Biochem Biophys. 2012 Oct;49(5):306- 15.

10. Lopresti AL, Hood SD, Drummond PD. Multiple antidepressant
potential modes of action of curcumin: a review of its anti-inflammatory, monoaminergic, antioxidant, immune-modulating and neuroprotective effects. J Psychopharmacol. 2012 Dec;26(12):1512-24.

11. Narumoto O, Matsuo Y, Sakaguchi M, Shoji S, Yamashita N,
Schubert D, Abe K, Horiguchi K, Nagase T, Yamashita N. Suppressive effects of a pyrazole derivative of curcumin on airway inflammation and remodeling. Exp Mol Pathol. 2012 Aug;93(1):18-25.

 

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.